| Yla-Herttuala |
In vivo SPECT/CT imaging of human orthotopic ovarian carcinoma xenografts with 111In-labeled monoclonal antibodies. |
| Plasmid Factory |
Transgene expression of transfected supercoiled plasmid DNA concatemers in mammalian cells. |
| Genosafe |
Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy. |
| Yla-Herttuala |
Eight-year safety follow-up of coronary artery disease patients after local intracoronary VEGF gene transfer. |
| Aiuti |
Revertant T lymphocytes in a patient with Wiskott-Aldrich syndrome: analysis of function and distribution in lymphoid organs. |
| Aiuti |
New insights into the pathogenesis of adenosine deaminase-severe combined immunodeficiency and progress in gene therapy. |
| Aiuti |
Evidence for long-term efficacy and safety of gene therapy for Wiskott-Aldrich syndrome in preclinical models. |
| Aiuti |
Recent advances in understanding the pathophysiology of Wiskott-Aldrich syndrome. |
| Aiuti |
Ten years of gene therapy for primary immune deficiencies. |
| Aiuti |
Comprehensive genomic access to vector integration in clinical gene therapy. |
| Cartier |
Hematopoietic stem cell transplantation and hematopoietic stem cell gene therapy in X-linked adrenoleukodystrophy. |
| Scherman |
Generation of high-titer neutralizing antibodies against botulinum toxins A, B, and E by DNA electrotransfer. |
| Scherman |
Widespread biochemical correction of murine mucopolysaccharidosis type VII pathology by liver hydrodynamic plasmid delivery. |
| Scherman |
A comparison of synthetic oligodeoxynucleotides, DNA fragments and AAV-1 for targeted episomal and chromosomal gene repair. |
| Scherman |
Effects of ciliary muscle plasmid electrotransfer of TNF-alpha soluble receptor variants in experimental uveitis. |
| Scherman |
Skin-specific promoters for genetic immunisation by DNA electroporation. |
| Scherman |
Amphiphilic perfluoroalkyl carbohydrates as new tools for liver imaging. |
| Scherman |
Iminothiol/thiourea tautomeric equilibrium in thiourea lipids impacts DNA compaction by inducing a cationic nucleation for complex assembly. |
| Scherman |
Evaluation of the muscle gene transfer activity of a series of amphiphilic triblock copolymers. |
| Scherman |
Comparative gene transfer between cationic and thiourea lipoplexes. |
| Scherman |
Advantages of bioluminescence imaging to follow siRNA or chemotherapeutic treatments in osteosarcoma preclinical models. |
| Scherman |
pFARs, plasmids free of antibiotic resistance markers, display high-level transgene expression in muscle, skin and tumour cells. |
| Scherman |
Lipopolythiourea/DNA interaction: a biophysical study. |
| Scherman |
Nucleic acid transfer with hemifluorinated polycationic lipids. |
| Scherman |
Design and evaluation of histidine-rich amphipathic peptides for siRNA delivery. |
| Panet |
Thermosensitivity of the reverse transcription process as an inactivation mechanism of lentiviral vectors. |
| Panet |
The oncolytic activity of Newcastle disease virus NDV-HUJ on chemoresistant primary melanoma cells is dependent on the proapoptotic activity of the inhibitor of apoptosis protein Livin. |
| Panet |
Herpes simplex virus delivery to orthotopic rectal carcinoma results in an efficient and selective antitumor effect. |
| Mir |
Nucleic acids electrotransfer-based gene therapy (electrogenetherapy): past, current, and future. |
| Mir |
Electroporating fields target oxidatively damaged areas in the cell membrane. |
| Mermod |
Protein-binding microarrays: probing disease markers at the interface of proteomics and genomics. |
| Mermod |
Transcription factor CTF1 acts as a chromatin domain boundary that shields human telomeric genes from silencing. |
| Mermod |
MAR elements regulate the probability of epigenetic switching between active and inactive gene expression. |
| Mermod |
Gene-mediated restoration of normal myofiber elasticity in dystrophic muscles. |
| Merten |
Evidence for long-term efficacy and safety of gene therapy for Wiskott-Aldrich syndrome in preclinical models. |
| Merten |
Insertional transformation of hematopoietic cells by self-inactivating lentiviral and gammaretroviral vectors. |
| Kochanek |
Adenovirus Vector Production and Purification. |
| Klatzmann |
High diversity of the immune repertoire in humanized NOD.SCID.gamma c-/- mice. |
| von Kalle Christof |
Sleeping beauty transposition from nonintegrating lentivirus. |
| von Kalle Christof |
The inherent differentiation program of short-term hematopoietic repopulating cells changes during human ontogeny. |
| von Kalle Christof |
Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy. |
| von Kalle Christof |
Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease. |
| von Kalle Christof |
Retroviral vector performance in defined chromosomal Loci of modular packaging cell lines. |
| von Kalle Christof |
Hematopoietic activity of human short-term repopulating cells in mobilized peripheral blood cell transplants is restricted to the first 5 months after transplantation. |
| Jacobs Andreas |
Patient-tailored, imaging-guided, long-term temozolomide chemotherapy in patients with glioblastoma. |
| Jacobs Andreas |
Molecular imaging of gliomas. |
| Jacobs Andreas |
Methods to monitor gene therapy with molecular imaging. |
| Hauser Hansjörg |
Generation of anti-TLR2 intrabody mediating inhibition of macrophage surface TLR2 expression and TLR2-driven cell activation. |
| Hauser Hansjörg |
ZrO(HPO(4))(1-x)(FMN)(x): quick and easy synthesis of a nanoscale luminescent biomarker. |
| Hauser Hansjörg |
Efficient generation of clinical-grade genetically modified dendritic cells for presentation of multiple tumor-associated proteins. |
| Hauser Hansjörg |
Quality of Cell Products: Authenticity, Identity, Genomic Stability and Status of Differentiation. |
| Hauser Hansjörg |
Timing and targeting of cell-based VEGF165 gene expression in ischemic tissue. |
| Hauser Hansjörg |
Bone formation in trabecular bone cell seeded scaffolds used for reconstruction of the rat mandible. |
| Hauser Hansjörg |
Effect of seeding technique and scaffold material on bone formation in tissue-engineered constructs. |
| Hauser Hansjörg |
Retroviral vector performance in defined chromosomal Loci of modular packaging cell lines. |
| Hauser Hansjörg |
A new PG13-based packaging cell line for stable production of clinical-grade self-inactivating gamma-retroviral vectors using targeted integration. |
| Hauser Hansjörg |
Synthetic gene regulation circuits for control of cell expansion. |
| Hauser Hansjörg |
Recombinant protein expression by targeting pre-selected chromosomal loci. |
| Hauser Hansjörg |
Precise regulation of transgene expression level and control of cell physiology. |
| Hauser Hansjörg |
Timing and targeting of cell-based VEGF165 gene expression in ischemic tissue. |
| Gänsbacher |
In vivo analysis of retroviral gene transfer to chondrocytes within collagen scaffolds for the treatment of osteochondral defects. |
| Gänsbacher |
Impact of radiation therapy on the oncolytic adenovirus dl520: implications on the treatment of glioblastoma. |
| Gänsbacher |
Efficient and stable gene transfer of growth factors into chondrogenic cells and primary articular chondrocytes using a VSV.G pseudotyped retroviral vector. |
| Gänsbacher |
GDNF-transduced Schwann cell grafts enhance regeneration of erectile nerves. |
| Gänsbacher |
Good news on the clinical gene transfer front. |
| Gänsbacher |
Searching for the right timing of surgical delay: angiogenesis, vascular endothelial growth factor and perfusion changes in a skin-flap model. |
| Gänsbacher |
Non-viral VEGF(165) gene therapy--magnetofection of acoustically active magnetic lipospheres ('magnetobubbles') increases tissue survival in an oversized skin flap model. |
| Gänsbacher |
The influence of the stable expression of BMP2 in fibrin clots on the remodelling and repair of osteochondral defects. |
| Gänsbacher |
Physicobiochemical synergism through gene therapy and functional tissue engineering for in vitro chondrogenesis. |
| Gänsbacher |
Adenovirus-based virotherapy enabled by cellular YB-1 expression in vitro and in vivo. |
| Gänsbacher |
Combined reporter gene PET and iron oxide MRI for monitoring survival and localization of transplanted cells in the rat heart. |
| Gänsbacher |
Therapeutic vaccination with an interleukin-2-interferon-gamma-secreting allogeneic tumor vaccine in patients with progressive castration-resistant prostate cancer: a phase I/II trial. |
| Gänsbacher |
Tissue engineering of the anterior cruciate ligament-sodium dodecyl sulfate-acellularized and revitalized tendons are inferior to native tendons. |
| Gänsbacher |
Cancer gene therapy: present and future. |
| Gänsbacher |
Tissue inhibitor of metalloproteinases-1-induced scattered liver metastasis is mediated by host-derived urokinase-type plasminogen activator. |
| Gänsbacher |
Reporter gene PET for monitoring survival of transplanted endothelial progenitor cells in the rat heart after pretreatment with VEGF and atorvastatin. |
| Gänsbacher |
Tetracycline-regulated bone morphogenetic protein 2 gene expression in lentivirally transduced primary rabbit chondrocytes for treatment of cartilage defects. |
| Gahrton Gösta |
Natural killer cell-based immunotherapy in cancer: current insights and future prospects. |
| Gahrton Gösta |
Impact of chromosome 13 deletion and plasma cell load on long-term survival of patients with multiple myeloma undergoing autologous transplantation. |
| Gahrton Gösta |
Retroviral gene transfer into primary human natural killer cells. |
| Gahrton Gösta |
Safety analysis of ex vivo-expanded NK and NK-like T cells administered to cancer patients: a phase I clinical study. |
| Dickson George |
Lentiviral-mediated genetic correction of hematopoietic and mesenchymal progenitor cells from Fanconi anemia patients. |
| Dickson George |
Integration-deficient lentiviral vectors: a slow coming of age. |
| Dickson George |
Comprehensive genomic access to vector integration in clinical gene therapy. |
| Dickson George |
The COX-2 inhibitors, meloxicam and nimesulide, suppress neurogenesis in the adult mouse brain. |
| Dickson George |
The identification of chromosomal translocation, t(4;6)(q22;q15), in prostate cancer. |
| Dickson George |
Design of phosphorodiamidate morpholino oligomers (PMOs) for the induction of exon skipping of the human DMD gene. |
| Dickson George |
Adenovirus vector vaccination induces expansion of memory CD4 T cells with a mucosal homing phenotype that are readily susceptible to HIV-1. |
| Dickson George |
Efficient liver-directed gene transfer by in situ generation of retroviral vector from adenoviral templates. |
| Dickson George |
Dosing regimen has a significant impact on the efficiency of morpholino oligomer-induced exon skipping in mdx mice. |
| Dickson George |
Gene therapy for muscular dystrophy: current progress and future prospects. |
| Dickson George |
Preliminary evaluation of a self-complementary AAV2/8 vector for hepatic gene transfer of human apoE3 to inhibit atherosclerotic lesion development in apoE-deficient mice. |
| Dickson George |
Molecular, cellular and physiological investigation of myostatin propeptide-mediated muscle growth in adult mice. |
| Carrondo |
Stabilization of gammaretroviral and lentiviral vectors: from production to gene transfer. |
| Carrondo |
Retroviral vector production under serum deprivation: The role of lipids. |
| Carrondo |
Thermosensitivity of the reverse transcription process as an inactivation mechanism of lentiviral vectors. |
| Carrondo |
Adenovirus Vector Production and Purification. |
| Cichutek Klaus |
Functional HIV-2- and SIVsmmPBj- derived lentiviral vectors generated by a novel polymerase chain reaction-based approach. |
| Cichutek Klaus |
Interaction of Vpx and apolipoprotein B mRNA-editing catalytic polypeptide 3 family member A (APOBEC3A) correlates with efficient lentivirus infection of monocytes. |
| Cichutek Klaus |
The US and EU regulatory perspectives on the clinical use of hematopoietic stem/progenitor cells genetically modified ex vivo by retroviral vectors |
| Cichutek Klaus |
Lentiviral vectors with measles virus glycoproteins - dream team for gene transfer? |
| Cichutek Klaus |
Restriction of HIV-1 replication in monocytes is abolished by Vpx of SIVsmmPBj. |
| Cichutek Klaus |
Pseudotyping lentiviral vectors with the wild-type measles virus glycoproteins improves titer and selectivity. |
| Bubenik |
Genetically modified vaccines augment the efficacy of cancer surgery and chemotherapy. |
| Bubenik |
Genetically modified cellular vaccines against human papillomavirus type 16 (HPV16)-associated tumors: adjuvant treatment of minimal residual disease after surgery/chemotherapy. |
| Bubenik |
HPV 16-associated tumours: IL-12 can repair the absence of cytotoxic and proliferative responses of tumour infiltrating cells after chemotherapy. |
| Bubenik |
Therapy for minimal residual tumor disease: beta-galactosylceramide inhibits the growth of recurrent HPV16-associated neoplasms after surgery and chemotherapy. |
| Bubenik |
Induction of protective immunity against MHC class I-deficient, HPV16-associated tumours with peptide and dendritic cell-based vaccines. |
| Bosch |
Deficiency of CB2 cannabinoid receptor in mice improves insulin sensitivity but increases food intake and obesity with age. |
| Bosch |
Endothelial cell transduction in primary cultures from regressing mesonephros. |
| Bosch |
Characterization of a recombinant adeno-associated virus type 2 Reference Standard Material. |
| Bosch |
Production, Purification and Characterization of Adeno-Associated Vectors. |
| Bosch |
EuroPhenome: a repository for high-throughput mouse phenotyping data. |
| Bosch |
Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats. |
| Bosch |
Skeletal muscle metabolism in the pathology and treatment of type 1 diabetes. |
| Bosch |
High AAV vector purity results in serotype- and tissue-independent enhancement of transduction efficiency. |
| Bosch |
Overexpression of kinase-negative protein kinase Cdelta in pancreatic beta-cells protects mice from diet-induced glucose intolerance and beta-cell dysfunction. |
| Bosch |
Scavenger function of resident autofluorescent perivascular macrophages and their contribution to the maintenance of the blood-retinal barrier. |
| Bosch |
Phosphofructo-1-kinase deficiency leads to a severe cardiac and hematological disorder in addition to skeletal muscle glycogenosis. |
| Bosch |
Gene and cellular therapy in Spain: moving forward. |
| Bosch |
Increased intraocular insulin-like growth factor-I triggers blood-retinal barrier breakdown. |
| Bosch |
Inducible adeno-associated virus vectors promote functional angiogenesis in adult organisms via regulated vascular endothelial growth factor expression. |
| Baum |
Retroviral vector performance in defined chromosomal Loci of modular packaging cell lines. |
| Baum |
A new PG13-based packaging cell line for stable production of clinical-grade self-inactivating gamma-retroviral vectors using targeted integration. |
| Baum |
Mechanisms controlling titer and expression of bidirectional lentiviral and gammaretroviral vectors. |
| Baum |
Limited complementarity between U1 snRNA and a retroviral 5' splice site permits its attenuation via RNA secondary structure. |
| Baum |
Gene therapy of MPL deficiency: challenging balance between leukemia and pancytopenia. |
| Baum |
Genotoxic potential of lineage-specific lentivirus vectors carrying the beta-globin locus control region. |
| Baum |
Insertional transformation of hematopoietic cells by self-inactivating lentiviral and gammaretroviral vectors. |
| Baum |
Cell-intrinsic and vector-related properties cooperate to determine the incidence and consequences of insertional mutagenesis. |
| Baum |
Protein Scaffold and Expression Level Determine Antiviral Activity of Membrane-Anchored Antiviral Peptides. |
| Baum |
Ectopic HOXB4 overcomes the inhibitory effect of tumor necrosis factor-{alpha} on Fanconi anemia hematopoietic stem and progenitor cells. |
| Baum |
Transcriptional enhancers induce insertional gene deregulation independently from the vector type and design. |
| Auricchio |
Different serum enzyme levels are required to rescue the various systemic features of the mucopolysaccharidoses. |
| Auricchio |
Abnormal autophagy, ubiquitination, inflammation and apoptosis are dependent upon lysosomal storage and are useful biomarkers of mucopolysaccharidosis VI. |
| Auricchio |
Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial. |
| Auricchio |
Isolation and evaluation of novel adeno-associated virus sequences from porcine tissues. |
| Ali Robin |
Cell transplantation strategies for retinal repair. |
| Ali Robin |
Targeted disruption of outer limiting membrane junctional proteins (Crb1 and ZO-1) increases integration of transplanted photoreceptor precursors into the adult wild-type and degenerating retina. |
| Ali Robin |
Adult ciliary epithelial cells, previously identified as retinal stem cells with potential for retinal repair, fail to differentiate into new rod photoreceptors. |
| Ali Robin |
Comprehensive genomic access to vector integration in clinical gene therapy. |
| Ali Robin |
AAV-mediated knockdown of peripherin-2 in vivo using miRNA-based hairpins. |
| Ali Robin |
Gene therapy in the second eye of RPE65-deficient dogs improves retinal function. |
| Cohen Haguenauer Odile |
En route to ethical recommendations for gene transfer clinical trials. |
| Cohen Haguenauer Odile |
Opinion paper on the current status of the regulation of gene therapy in Europe. |
| Cohen Haguenauer Odile |
In vivo repopulation ability of genetically corrected bone marrow cells from Fanconi anemia patients. |
| Cohen Haguenauer Odile |
Comprehensive genomic access to vector integration in clinical gene therapy. |
| Cohen Haguenauer Odile |
A one-step prescreening for point mutations and large rearrangement in BRCA1 and BRCA2 genes using quantitative polymerase chain reaction and high-resolution melting curve analysis. |
| Cohen Haguenauer Odile |
Toward a Proportionate Regulatory Framework for Gene Transfer: A Patient Group-Led Initiative. |
| Cohen Haguenauer Odile |
Relevance of an Academic GMP Pan-European Vector Infra-structure (PEVI). |
| ALI Robin |
Bilateral adrenalectomy in treatment of disseminated breast cancer. |
